South Africa has begun rolling out a new line of defense against HIV: a six-monthly preventive injection that is now available free of charge at hundreds of public health facilities. The anti-HIV jab, which prevents HIV through sex, is currently stocked at 360 government clinics across six provinces, according to the health department’s list of clinics. The provinces included in the initial rollout are Gauteng, KwaZulu-Natal, the Eastern Cape, Mpumalanga, North West and the Western Cape. The Northern Cape, Limpopo and the…

South Africa will begin offering the twice-yearly HIV prevention shot lenacapavir (LEN) on June 5, Health Minister Aaron Motsoaledi announced, hailing a major step forward in the fight against the virus. For individuals who are HIV-negative, the long-acting injection has proven to be almost completely effective at preventing sexual transmission. But new drugs alone won’t end the epidemic, argue Mitchell Warren, executive director of the international health advocacy group AVAC, and Wawira Nyagah, executive director of…

Paediatric HIV cure research is yielding cautious optimism: very early antiretroviral therapy (ART) can, in some children, produce periods of ART-free remission — a state in which the virus remains undetectable without ongoing medication — but it has not delivered full viral eradication, researchers say. The long quest for a cure has been complicated by HIV’s capacity to mutate and hide in long-lived viral reservoirs, a challenge that has confounded scientists for more than four decades, reports Sethi Ncube for allAfrica.…

HARARE — A group of public health physicians urged Harare and Washington on Thursday to resume negotiations after the collapse of a proposed $367 million bilateral health agreement that health experts say would have strengthened Zimbabwe's fragile health system. The proposed package, officials and health specialists said, was aimed at bolstering priority programs including HIV/AIDS treatment and prevention, tuberculosis control, malaria response, maternal and child health services and disease outbreak preparedness. Its…

Cape Town — An African-led effort to develop an HIV vaccine has launched a clinical trial at the Desmond Tutu Health Foundation in Cape Town, organizers announced, with the first participant already enrolled. The study, called BRILLIANT 011 and led by The BRILLIANT Consortium, is being conducted by the South African Medical Research Council (SAMRC) and is designed to target the strains of HIV that are circulating in Southern Africa. "The trial is...marking a major milestone in African-led HIV vaccine research. BRILLIANT…

UNAIDS Warns of Deteriorating HIV Services Amid Funding Crisis Abrupt funding cuts and deteriorating human rights conditions have disrupted HIV prevention and treatment services across dozens of countries, UNAIDS has warned. In a stark report released to mark World AIDS Day, the UN agency highlighted a troubling trend: international assistance for HIV programs has sharply declined, with projections indicating that external health funding could plummet by 30-40% by 2025 compared to 2023 levels. The agency's Executive…

Long-acting HIV injection at $40 could reshape prevention — if the world can deliver it A potentially seismic shift in HIV prevention is quietly taking shape: a twice-yearly injectable drug, lenacapavir, has won backing from global health partners and is slated to be available to more than 100 low- and middle-income countries within the next two years — at a price that would make it accessible to millions. Under an agreement brokered by the Clinton Health Access Initiative with support from the Bill & Melinda Gates…

South Africa at a Crossroads: Donor Cuts Threaten Hard‑Won Gains Against HIV GAUTENG, South Africa — In a conference hall a short drive from Johannesburg’s busy highways, the blunt arithmetic of global aid collided with the realities faced by clinics and families. Scientists, clinicians, activists and people living with HIV spoke in urgent, sometimes angry tones: the era of steady international support that helped turn a tide against HIV may be ebbing, and the consequences could be catastrophic. Stark projections, stark…

In the vibrant neighborhoods of Epworth and Mbare in Harare, Doctors Without Borders (MSF) has embarked on a crucial mission: empowering the youth to confront mental health issues through a unique peer-led initiative. Equipped with specialized training, educators affiliated with MSF deliver essential psychological first aid. They bridge young individuals with critical mental health resources, encompassing a range of services such as medical care, HIV testing, STI management, contraceptive options, health education,…

In the vibrant city of Lima, Peru, allAfrica's very own Sethi Ncube is immersing herself in the dynamic world of HIV research at the auspicious 5th HIV Research for Prevention Conference (HIVR4P 2024). This unique gathering is a monumental global platform specifically devoted to the intricate and rapidly evolving field of HIV prevention research. During this event, scientists, healthcare professionals, and policy makers from around the world converge to exchange innovative ideas and present transformative findings. Ncube is…